Colorectal carcinoma (CRC) is a major cause of morbidity and mortality in Western countries.It has so far been molecularly defined mainly by alterations of the Wnt pathway.We show here for the first time that aberrant activities of the signal transducer and activator of transcription STAT3 actively contribute to this malignancy and, thus, are a pot
From Syria via Turkey and Greece to ultimately Ireland, it has been a very long journey full of ups and downs, tears of frustration and dismay, the odd Bike Racks glimmer of hope.Eleven months on roads and cross country, living in tents and the odd night under a proper roof, it was a long and tortuous road that finally took me and 129 other Syrians
The article considers peer review as the main procedure for demarcating scientific knowledge from other kinds thereof, which do not meet the criteria set for research results.The authors examine the history of peer review, which has first been used in early scientific journals and then has become one of the key approaches to distributing funds for
Oxidative stress promotes T.cruzi growth and development of chronic Chagas heart dysfunction.However, the literature contains gaps that must be fulfilled, largely due to variations in parasite DTU sources, cell types, mouse strains, and tools to manipulate redox status.We assessed the impact of oxidative environment on parasite burden in cardiomyob
This paper uses household-level data from a nationally representative survey conducted in 2009 and 2010 in Bangladesh to determine the relationship between coping mechanisms and having access to credits.The analysis finds that more than half of the sample claimed to have faced shocks over the years.The paper also discusses the coping strategies hou